Thermo Fisher Scientific Nurr1 Polyclonal Antibody
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카탈로그 번호 | CAS 번호 | 설명 | 상태 | 단위 | 판매가 | 할인가 | 가격(VAT포함) | 수량 / 장바구니 / 찜 |
A0142540 | - | Thermo Fisher Scientific A0142540 Nurr1 Polyclonal Antibody 40 ug pk | 재고문의 | pk | 0원 | - | 0원 |
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Applications
Tested Dilution
Publications
Western Blot (WB)
1-2 µg/mL
Product Specifications
Host/Isotype
Rabbit / IgG
Class
Polyclonal
Type
Antibody
Immunogen
KLH-coupled synthetic peptide within residues 310~360 of human Nurr1 protein (Swiss Prot: P43354) if (typeof window.$mangular === undefined
|| !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{
targetFamily:
Nurr1,
uniProtId:
P43354-1,
ncbiNodeId:
9606,
antigenRange:
310-360,
antigenLength:
598,
antigenImageFileName:
A01425-40_Nurr1_P43354-1_Rabbit.svg,
antigenImageFileNamePDP:
A01425-40_Nurr1_P43354-1_Rabbit_PDP.jpeg,
sortOrder:
1}\]
; $mangular.isB2BCMGT = false
; $mangular.isEpitopesModalImageMultiSizeEnabled = true
;
View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}
Conjugate
Unconjugated Unconjugated Unconjugated
Form
Lyophilized
Storage conditions
-20°C or -80°C if preferred
Shipping conditions
Wet ice
Product Specific Information
Reconstitute the lyophilized powder with deionized water (or equivalent) to an antibody concentration of 0.5 mg/ml.
Nurr1 is a transcription factor and belongs to the Nur77 family of orphan receptors. This family of transcription factors plays key roles in the development and the effector functions of T lymphocytes. Nurr1 promote signaling via its heterodimerization partner, the retinoid X receptor (RXR). Nurr1 protein is expressed in the embryonic ventral midbrain and it is critical for the development of dopamine neurons. In addition, Nurr1 has been implicated in the maintenance of adult dopaminergic neurons.GenScript Nurr1 Antibody, pAb, Rabbit is developed in rabbit using a KLH-coupled synthetic peptide within residues 310~360 of human Nurr1 protein (Swiss Prot: P43354).
Target Information
The Nuclear receptor related 1 protein (Nurr1) also known as NR4A2 (nuclear receptor subfamily 4, group A, member 2) is a protein that in humans is encoded by the NR4A2 gene. NURR1 is a member of the nuclear receptor family of intracellular transcription factors.Nurr1 plays a key role in the maintenance of the dopaminergic system of the brain. Mutations in this gene have been associated with disorders related to dopaminergic dysfunction, including Parkinson`s disease, schizophrenia, and manic depression. Misregulation of this gene may be associated with rheumatoid arthritis. Four transcript variants encoding four distinct isoforms have been identified for this gene. Additional alternate splice variants may exist, but their full-length nature has not been determined.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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