Thermo Fisher Scientific Synapsin 1 Polyclonal Antibody
Synapsin 1 단백질에 특이적인 Thermo Fisher Scientific의 Rabbit Polyclonal 항체. WB, IHC, ICC/IF, IP 등 다양한 응용에 적합. Lyophilized 형태로 제공되며 -20°C에서 보관. 신경세포 시냅스 관련 단백질 연구에 유용.
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:1,000 | View 1 publication |
| Immunohistochemistry (IHC) | 1:2,000 | - |
| Immunocytochemistry (ICC/IF) | 1:1,000–1:2,000 | - |
| Immunoprecipitation (IP) | 1 µg / 200 µg lysate | - |
Product Specifications
| Specification | Description |
|---|---|
| Published Species | Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Native protein purified from bovine brain |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_561585 |
Product Specific Information
This antibody is specific for the ~78 kDa Synapsin I protein doublet. Immunolabeling is blocked by preadsorption of the antibody with the protein used to generate the antibody.
Reconstitute with 50 µL of PBS.
Target Information
SYN1 (synapsin 1) is a member of the synapsin gene family. Synapsins encode neuronal phosphoproteins that associate with the cytoplasmic surface of synaptic vesicles. Family members share common protein domains and are implicated in synaptogenesis and modulation of neurotransmitter release, suggesting a potential role in several neuropsychiatric diseases.
Synapsin 1 is involved in regulation of axonogenesis and synaptogenesis. It serves as a substrate for several different protein kinases, and phosphorylation may regulate its function in the nerve terminal. Mutations in this gene may be associated with X-linked neuronal degeneration disorders such as Rett syndrome. Alternatively spliced transcript variants encoding different isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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