Thermo Fisher Scientific NF1 Monoclonal Antibody (McNFn27a)
NF1 단백질을 검출하는 mouse monoclonal antibody로, Human, Mouse, Rat 시료에 반응합니다. Western blot, ICC/IF, ELISA, IP 등 다양한 응용에 적합하며, Protein G로 정제된 액상형 제품입니다. 1 mg/mL 농도, PBS/BSA buffer에 보관하며 연구용으로만 사용됩니다.
- 카탈로그번호
- MA1084
- 판매단위
- pk
카탈로그
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 5–10 µg/mL |
| Immunocytochemistry (ICC/IF) | 2 µg/mL |
| ELISA | Assay-dependent |
| Immunoprecipitation (IP) | Assay-dependent |
| Affinity Purification (AP) | Assay-dependent |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | McNFn27a |
| Immunogen | Synthetic peptide corresponding to the N-terminal residues 27–41 of human neurofibromin |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein G |
| Storage Buffer | PBS with 1 mg/mL BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | −20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_560294 |
Product Specific Information
MA1-084 detects neurofibromin in human, rat, and mouse cells.
It has been successfully used in Western blot procedures, detecting a ~230–260 kDa protein.
The immunogen is a synthetic peptide corresponding to the N-terminal residues 27–41 of human neurofibromin.
Target Information
The protein encoded by this gene is a type I integral membrane protein localized in the intermediate region between the endoplasmic reticulum and the Golgi apparatus, presumably recycling between the two compartments.
It is a mannose-specific lectin and a member of a novel family of plant lectin homologs in the secretory pathway of animal cells.
Mutations in this gene are associated with a coagulation defect. The gene was identified as responsible for combined factor V-factor VIII deficiency, a rare autosomal recessive disorder in which both coagulation factors V and VIII are diminished.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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