Thermo Fisher Scientific CENPJ Polyclonal Antibody, MaxPab

Applications

Tested Dilution

Publications

Western Blot (WB)

1-5 µg/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

CENPJ (AAH24209.3, 1 a.a. approximately 372 a.a) full-length human protein. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:CENPJ,uniProtId:Q9HC77-1,ncbiNodeId:9606,antigenRange:1-1338,antigenLength:1338,antigenImageFileName:H00055835-D01P_CENPJ_Q9HC77-1_Rabbit.svg,antigenImageFileNamePDP:H00055835-D01P_CENPJ_Q9HC77-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

See Label

Purification

Affinity chromatography

Storage buffer

PBS, pH 7.4

Contains

no preservative

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

Product Specific Information

Sequence of this protein is as follows: MRKLQKERKV FEKYTTAART FPDKKEREEI QTLKQQIADL REDLKRKETK WSSTHSRLRS QIQMLVRENT DLREEIKVME RFRLDAWKRA EAIESSLEVE KKDKLANTSV RFQNSQISSG TQVEKYKKNY LPMQGNPPRR SKSAPPRDLG NLDKGQAASP REPLEPLNFP DPEYKEEEED QDIQGEISHP DGKVEKVYKN GCRVILFPNG TRKEVSADGK TITVTFFNGD VKQVMPDQRV IYYYAAAQTT HTTYPEGLEV LHFSSGQIEK HYPDGRKEIT FPDQTVKNLF PDGQEESIFP DGTIVRVQRD GNKLIEFNNG QRELHTAQFK RREYPDGTVK TVYANGHQET KYRSGRIRVK DKEGNVLMDT EL

Target Information

This gene encodes a protein that belongs to the centromere protein family. During cell division, this protein plays a structural role in the maintenance of centrosome integrity and normal spindle morphology, and it is involved in microtubule disassembly at the centrosome. This protein can function as a transcriptional coactivator in the Stat5 signaling pathway, and also as a coactivator of NF-kappaB-mediated transcription, likely via its interaction with the coactivator p300/CREB-binding protein. Mutations in this gene are associated with primary autosomal recessive microcephaly, a disorder characterized by severely reduced brain size and mental retardation.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.