Thermo Fisher Scientific CENPJ Polyclonal Antibody, MaxPab

Applications

• Western Blot (WB): 1–5 µg/mL

Product Specifications

Product Specific Information

Sequence of this protein is as follows:
MRKLQKERKV FEKYTTAART FPDKKEREEI QTLKQQIADL REDLKRKETK WSSTHSRLRS QIQMLVRENT DLREEIKVME RFRLDAWKRA EAIESSLEVE KKDKLANTSV RFQNSQISSG TQVEKYKKNY LPMQGNPPRR SKSAPPRDLG NLDKGQAASP REPLEPLNFP DPEYKEEEED QDIQGEISHP DGKVEKVYKN GCRVILFPNG TRKEVSADGK TITVTFFNGD VKQVMPDQRV IYYYAAAQTT HTTYPEGLEV LHFSSGQIEK HYPDGRKEIT FPDQTVKNLF PDGQEESIFP DGTIVRVQRD GNKLIEFNNG QRELHTAQFK RREYPDGTVK TVYANGHQET KYRSGRIRVK DKEGNVLMDT EL

Target Information

This gene encodes a protein belonging to the centromere protein family. During cell division, it plays a structural role in maintaining centrosome integrity and spindle morphology and is involved in microtubule disassembly at the centrosome.
It also functions as a transcriptional coactivator in the Stat5 signaling pathway and as a coactivator of NF-kappaB-mediated transcription through interaction with p300/CREB-binding protein.
Mutations in this gene are associated with primary autosomal recessive microcephaly, characterized by reduced brain size and mental retardation.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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