Thermo Fisher Scientific CENPJ Monoclonal Antibody (1A5)
CENPJ 단백질을 인식하는 Mouse monoclonal antibody로 Western blot 및 ELISA에 적합. 인간 시료에 반응하며 비결합(Unconjugated) 형태로 제공. 세포분열 시 중심체 구조 유지 연구에 유용. 연구용으로만 사용 가능.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:1,000
ELISA
- Tested Dilution: 1:500–1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 1A5 |
| Immunogen | CENPJ (NP_060921, 979 a.a. – approximately 1088 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Storage buffer | Ascites |
| Contains | No preservative |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Protein sequence:
KYTTAARTFP DKKEREEIQT LKQQIADLRE DLKRKETKWS STHSRLRSQI QMLVRENTDL
REEIKVMERF RLDAWKRAEA IESSLEVEKK DKLANTSVRF QNSQISSGTQTarget Information
This gene encodes a protein belonging to the centromere protein family.
During cell division, it plays a structural role in maintaining centrosome integrity and normal spindle morphology, and is involved in microtubule disassembly at the centrosome.
It can act as a transcriptional coactivator in the Stat5 signaling pathway and as a coactivator of NF-kappaB-mediated transcription, likely via interaction with the coactivator p300/CREB-binding protein.
Mutations in this gene are associated with primary autosomal recessive microcephaly, a disorder characterized by severely reduced brain size and mental retardation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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