Thermo Fisher Scientific Complement Factor Ba Monoclonal Antibody (014III-33.2.4.3)
인체 Complement Factor Ba를 인식하는 mouse monoclonal antibody. Western blot, IHC(F), Flow cytometry, ELISA, 기능 분석에 사용 가능. Protein A 정제, 1.1 mg/mL 농도의 액상 항체로 단기 4°C, 장기 -20°C 보관. 연구용으로만 사용.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | Assay-dependent |
| Immunohistochemistry (Frozen) (IHC (F)) | Assay-dependent |
| Flow Cytometry (Flow) | Assay-dependent |
| ELISA | Assay-dependent |
| Functional Assay | Assay-dependent |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 014III-33.2.4.3 |
| Immunogen | Purified human complement factor B |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.1 mg/mL |
| Purification | Protein A |
| Storage Buffer | BBS |
| Contains | 0.1% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2745073 |
Product Specific Information
This Mouse anti-Human Complement Factor B (Ba Fragment) monoclonal antibody (clone 014III-33.2.4.3) recognizes the 30 kDa Ba fragment of the 90 kDa human complement factor B present in blood serum. C3b associates with complement factor B, inducing conformational change.
Target Information
Complement Factor B (CFB) is associated with atypical hemolytic uremic syndrome type 4 (AHUS4), a complex genetic disorder characterized by microangiopathic hemolytic anemia, thrombocytopenia, and renal failure, without episodes of enterocolitis or diarrhea.
Atypical forms have poorer prognosis, higher mortality, and frequent progression to end-stage renal disease.
Disease susceptibility is linked to variations in complement cascade components or regulatory factors, and other genes may modify the phenotype.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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