Thermo Fisher Scientific Phospho-MAPKAPK2 (Thr334) Recombinant Rabbit Monoclonal Antibody (MAPKAPK2T334-H2)
Recombinant rabbit monoclonal antibody specific for phospho-MAPKAPK2 (Thr334). Validated for WB and Flow Cytometry. Offers high specificity, lot-to-lot consistency, and animal-free formulation. Suitable for studying MAPKAPK2-mediated stress and inflamm...
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Applications
Western Blot (WB)
- Tested Dilution: Assay-dependent
Flow Cytometry (Flow)
- Tested Dilution: 1–1,000 ng/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG, kappa |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | MAPKAPK2T334-H2 |
| Immunogen | Synthetic phospho-peptide corresponding to residues surrounding Thr334 of human phospho MAPKAPK-2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS (pH 7.4) with 50% glycerol, 0.1% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2745071 |
Additional Formats
Product Specific Information
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems developed by cloning specific antibody DNA sequences from immunoreactive rabbits. Individual clones are screened to select optimal candidates for production.
Advantages:
- High specificity and sensitivity
- Lot-to-lot consistency
- Animal origin-free formulation
- Broader immunoreactivity due to larger rabbit immune repertoire
Target Information
MAPKAPK2 mediates p38 and ERK signaling in vivo and is involved in stress and inflammatory responses, nuclear export, gene expression regulation, and cell proliferation. It encodes a member of the Ser/Thr protein kinase family and is regulated through direct phosphorylation by p38 MAP kinase. HSP27 is one of its known substrates. Two transcript variants encoding distinct isoforms have been identified for MAPKAPK2.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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