Thermo Fisher Scientific CD36 Monoclonal Antibody (eBioNL07 (NL07)), eBioscience
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카탈로그 번호 | CAS 번호 | 설명 | 상태 | 재고 | 단위 | 판매가 | 할인가 | 가격(VAT포함) | 수량 / 장바구니 / 찜 |
14-0369-37 | - | Thermo Fisher Scientific 14-0369-37 CD36 Monoclonal Antibody (eBioNL07 (NL07)), eBioscience 2 mg pk | 재고문의 | pk | 2,238,000원 | - | 2,461,800원 | ||
14-0369-82 | - | Thermo Fisher Scientific 14-0369-82 CD36 Monoclonal Antibody (eBioNL07 (NL07)), eBioscience 100 ug pk | 재고문의 | pk | 276,000원 | - | 303,600원 | ||
14-0369-80 | - | Thermo Fisher Scientific 14-0369-80 CD36 Monoclonal Antibody (eBioNL07 (NL07)), eBioscience 25 ug pk | 재고문의 | pk | 112,000원 | - | 123,200원 | ||
14-0369-95 | - | Thermo Fisher Scientific 14-0369-95 CD36 Monoclonal Antibody (eBioNL07 (NL07)), eBioscience 10 mg pk | 재고문의 | pk | 0원 | - | 0원 |
다른 상품 둘러보기
Applications
Tested Dilution
Publications
Immunohistochemistry (IHC)
-
View 2 publications 2 publications
Flow Cytometry (Flow)
0.5 µg/test
View 5 publications 5 publications
ChIP assay (ChIP)
-
View 1 publication 1 publication
Product Specifications
Species Reactivity
Human
Published species
Not Applicable
Host/Isotype
Mouse / IgM
Class
Monoclonal
Type
Antibody
Clone
eBioNL07 (NL07)
Conjugate
Unconjugated Unconjugated Unconjugated
View additional formats
Form
Liquid
Concentration
0.5 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.2
Contains
0.09% sodium azide
Storage conditions
4° C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2864870
Product Specific Information
Description: The monoclonal antibody eBioNL07 recognizes human CD36, which is a member of the class B scavenger receptor family. CD36 was originally identified as a platelet-membrane glycoprotein also called glycoprotein IV and a receptor for thrombospondin-1 (TSP-1) and extracellular matrix proteins. Binding to TSP-1 is in the CLESH (CD36 LIMP-II Emp sequence homology) domain of CD36. CD36 expression is broad and includes microvascular (but not large vessel) endothelium, adipocytes, skeletal muscle, dendritic cells, epithelia of the retina, breast, and intestine, smooth muscle cells, and hematopoietic cells, including erythroid precursors, platelets, monocytes/macrophages, DCs and megakaryocytes. Expression on platelets is absent on Nak^a negative donors. Unlike other scavenger receptor, CD36 binds LDL that has been exposed to minimally
oxidizing conditions. CD36 is also a fatty acid translocase (FAT) necessary for the transport of long-chain fatty acids (LCFAs) and therefore may play a role in atherosclerosis.
Applications Reported: This eBioNL07 (NL07) antibody has been reported for use in flow cytometric analysis.
Applications Tested: This eBioNL07 (NL07) antibody has been tested by flow cytometric analysis of human peripheral blood cells. This can be used at less than or equal to 0.5 µg per test. A test is defined as the amount (µg) of antibody that will stain a cell sample in a final volume of 100 µL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest.
Purity: Greater than 90%, as determined by SDS-PAGE.
Aggregation: Less than 10%, as determined by HPLC.
Filtration: 0.2 µm post-manufacturing filtered.
Target Information
CD36, also known as scavenger receptor class B member 3, is a protein that is expressed on the surface of various cell types, including macrophages, platelets, and adipocytes. It plays a role in lipid metabolism, inflammation, and atherosclerosis, and is involved in the recognition and uptake of various ligands such as oxidized low-density lipoproteins, long-chain fatty acids, and apoptotic cells. CD36 is also implicated in the pathogenesis of malaria. The protein encoded by this gene serves as a receptor for thrombospondin in platelets and various cell lines, and is the fourth major glycoprotein of the platelet surface. It binds to collagen, thrombospondin, anionic phospholipids, and oxidized LDL, and directly mediates cytoadherence of Plasmodium falciparum parasitized erythrocytes. Mutations in this gene cause platelet glycoprotein deficiency. Multiple alternatively spliced transcript variants have been found for this gene. Diseases associated with CD36 include Platelet Glycoprotein IV Deficiency and Coronary Heart Disease 7.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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