Thermo Fisher Scientific CD38 Monoclonal Antibody (HIT2), eBioscience
Human CD38 단백질을 인식하는 HIT2 클론 단일클론 항체로, Flow Cytometry 및 IHC에 최적화됨. Unconjugated 형태로 다양한 형광체 포맷 제공. 높은 순도(>90%) 및 낮은 응집도(<10%)를 보장하며, 연구용으로 적합.
- 카탈로그번호
- 14-0389-xx (3개 옵션)
- 판매단위
- pk
카탈로그
3개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific CD38 Monoclonal Antibody (HIT2), eBioscience
Thermo Fisher Scientific CD38 Monoclonal Antibody (HIT2), eBioscience
Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Immunohistochemistry (IHC) | - | 2 publications |
| Immunohistochemistry (Paraffin) (IHC (P)) | 40 µg/mL | - |
| Flow Cytometry (Flow) | 1 µg/test | 19 publications |
| ELISA | - | 1 publication |
| Miscellaneous PubMed | - | 1 publication |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Published Species | Human, Mouse |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | HIT2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.2 |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2864872 |
Available Conjugate Formats
- Alexa Fluor 700
- APC
- APC-eFluor 780
- Biotin
- Brilliant UV 805
- Brilliant Violet 421
- Brilliant Violet 480
- eFluor 450
- FITC
- PE
- PE-Cyanine5
- PE-Cyanine7
- PE-eFluor 610
- PerCP-eFluor 710
- Super Bright 436
- Super Bright 702
- Request custom conjugation
Product Specific Information
The HIT2 monoclonal antibody reacts with the human CD38 molecule, an approximately 45 kDa type II transmembrane protein. CD38 is expressed by thymocytes, peripheral B cells (including plasma cells), activated T cells, and monocytes. It acts as a counter-receptor for CD31 and exhibits cyclase and hydrolase enzymatic activity.
Applications Reported: Flow cytometric analysis and immunohistochemical staining.
Applications Tested:
- Flow cytometry: ≤1 µg/test (100 µL final volume; 10⁵–10⁸ cells/test).
- IHC (formalin-fixed paraffin embedded tissue): ≤40 µg/mL using low pH antigen retrieval.
Careful titration is recommended for optimal assay performance.
Purity: >90% (SDS-PAGE)
Aggregation: <10% (HPLC)
Filtration: 0.2 µm post-manufacturing filtered
Target Information
CD38 (NAD⁺ glycohydrolase) is a type II transmembrane glycoprotein involved in activation, proliferation, and differentiation of lymphocytes, as well as apoptosis mediation in progenitor cells. It functions as an ectoenzyme with ADP-ribosyl cyclase and cyclic ADP-ribose hydrolase activity, and serves as a surface receptor.
Antibodies to CD38 are useful for:
- Subtyping lymphomas and leukemias
- Detecting plasma cells (e.g., myeloma identification)
- Marking activated B and T cells
CD38 is highly expressed in pancreas, liver, kidney, malignant lymphoma, and neuroblastoma. Dysfunction is associated with chronic lymphocytic leukemia and Richter's Syndrome.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Thermo Fisher Scientific 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.