Thermo Fisher Scientific Phospho-DOK2 (Tyr402) Polyclonal Antibody
Phospho-DOK2 (Tyr402) 항체로, 인산화된 DOK2 단백질의 Tyr402 부위를 특이적으로 인식합니다. Western blot 및 IHC(P) 실험에 적합하며, 사람과 랫트 시료에서 반응합니다. Rabbit polyclonal 형식으로, 1 mg/mL 농도의 액상 제품입니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human DOK2 (Accession O60496), corresponding to amino acid residues around phosphorylated Tyr402. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Sequential chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2816835 |
Product Specific Information
Antibody detects endogenous levels of DOK2 only when phosphorylated at Tyr402.
Target Information
The protein encoded by this gene is constitutively tyrosine phosphorylated in hematopoietic progenitors isolated from chronic myelogenous leukemia (CML) patients in the chronic phase.
It may be a critical substrate for p210(bcr/abl), a chimeric protein associated with CML.
This encoded protein binds p120 from CML cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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