Thermo Fisher Scientific Phospho-AS160 (Ser570) Polyclonal Antibody
AS160 단백질의 Ser570 인산화 형태를 특이적으로 검출하는 Rabbit Polyclonal Antibody. Western blot 및 IHC에 적합하며, 인간·마우스·랫 반응성. 1 mg/mL 농도, PBS+50% glycerol 저장, -20°C 보관.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:2,000
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:50–1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human TBC1D4 (Accession O60343), corresponding to amino acid residues around phosphorylated Ser570 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Sequential chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2816833 |
Product Specific Information
Antibody detects endogenous levels of AS160 only when phosphorylated at Ser570.
Target Information
AS160 (TBC1D4) is a GTPase-activating protein for RAB2A, RAB8A, RAB10, and RAB14. The isoform 2 version of this protein promotes insulin-induced glucose transporter SLC2A4/GLUT4 translocation to the plasma membrane, increasing glucose uptake. Mutations in this gene are associated with Diabetes mellitus, non-insulin-dependent, type 5 (NIDDM5).
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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