Thermo Fisher Scientific Phospho-TLR5 (Ser805) Polyclonal Antibody
TLR5 단백질의 Ser805 인산화 형태를 특이적으로 검출하는 Rabbit Polyclonal Antibody. Western blot 및 IHC(P)에서 사용 가능. Human, Mouse, Rat 반응성. 고순도 정제, -20°C 보관, 연구용 전용.
✨AI 추천 연관 상품
AI가 분석한 이 상품과 연관된 추천 상품들을 확인해보세요
연관 상품을 찾고 있습니다...
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human TLR5 (Accession O60602), corresponding to amino acid residues around phosphorylated Ser805 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Sequential chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2816836 |
Product Specific Information
Antibody detects endogenous levels of TLR5 only when phosphorylated at Ser805.
Target Information
TLR5 is a Type I membrane protein belonging to the Toll-like receptor family, participating in the innate immune response to microbial agents. It mediates detection of bacterial flagellins and acts via MyD88 and TRAF6, leading to NF-κB activation, cytokine secretion, and the inflammatory response. TLR5 binds to TIRAP and MyD88 via their respective TIR domains. It is highly expressed in liver, detected in lung, and at very low levels in most other tissues. The TLR5 gene locus is associated with susceptibility to Salmonella. Mouse strains vary in resistance to S. typhimurium infection, classified as susceptible (BALB/c, C57BL/6, C3H/He), intermediate (DBA/2, C75L), and resistant (A, CBA). The MOLF/Ei strain is highly susceptible, has a unique TLR5 haplotype, and lower TLR5 expression. A common TLR5 stop codon polymorphism that disrupts signaling is associated with susceptibility to Legionnaires’ disease, underscoring TLR5’s role in innate immunity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
🏷️Thermo Fisher Scientific 상품 둘러보기
동일 브랜드의 다른 상품들을 확인해보세요
Thermo Fisher Scientific
Thermo Fisher Scientific Phospho-delta Catenin (Tyr96) Polyclonal Antibody
614,900원
Thermo Fisher Scientific
Thermo Fisher Scientific Phospho-delta Catenin (Tyr248) Polyclonal Antibody
614,900원
Thermo Fisher Scientific
Thermo Fisher Scientific Phospho-TLR5 (Ser805) Polyclonal Antibody
627,600원
Thermo Fisher Scientific
Thermo Fisher Scientific Phospho-DOK2 (Tyr402) Polyclonal Antibody
627,600원
Thermo Fisher Scientific
Thermo Fisher Scientific Phospho-HBP1 (Ser380) Polyclonal Antibody
627,600원
배송/결제/교환/반품 안내
배송 정보
| 기본 배송비 |
| 교환/반품 배송비 |
|
|---|---|---|---|
| 착불 배송비 |
| ||
| 교환/반품 배송비 |
| ||
결제 및 환불 안내
| 결제수단 |
|
|---|---|
| 취소 |
|
| 반품 |
|
| 환급 |
|
교환 및 반품 접수
| 교환 및 반품 접수 기한 |
|
|---|---|
| 교환 및 반품 접수가 가능한 경우 |
|
| 교환 및 반품 접수가 불가능한 경우 |
|
교환 및 반품 신청
| 교환 절차 |
|
|---|---|
| 반품 절차 |
|