Thermo Fisher Scientific Phospho-delta Catenin (Tyr248) Polyclonal Antibody
Phospho-delta Catenin (Tyr248)에 특이적인 Rabbit Polyclonal Antibody로, 인산화된 CTNND1 단백질 검출에 적합합니다. Western Blot, IHC, ICC/IF에 사용 가능하며, 액상 형태로 -20°C 보관합니다. 연구용으로만 사용 가능합니다.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human CTNND1 (Accession O60716), corresponding to amino acid residues around phosphorylated Tyr248 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2816837 |
Product Specific Information
Antibody detects endogenous levels of CTNND1 only when phosphorylated at Tyr248.
Target Information
Delta 1 Catenin is an efficient tyrosine kinase substrate implicated both in cell transformation by SRC and in ligand-induced receptor signaling through the EGF, PDGF, CSF-1, and ERBB2 receptors.
The association of catenins to cadherins produces a complex which is linked to the actin filament network, and which seems to be of primary importance for cadherins cell-adhesion properties.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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