Thermo Fisher Scientific HCCS Polyclonal Antibody
HCCS 단백질을 인식하는 토끼 폴리클로날 항체로, Western blot, IHC, ICC/IF 등 다양한 응용에 적합합니다. 인간, 마우스, 랫트에 반응하며, 항원 친화 크로마토그래피로 정제되었습니다. 연구용으로만 사용 가능합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:1,000
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:50–1:200
Immunocytochemistry (ICC/IF)
- Tested Dilution: 1:50–1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host/Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to amino acids 80–120 of Human HCCS |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2 |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2719106 |
Product Specific Information
The antibody was affinity-purified from rabbit antiserum by affinity chromatography using epitope-specific immunogen. The purity is >95% (by SDS-PAGE).
Target Information
CCHL (cytochrome c-type heme lyase), also known as HCCS (holocytochrome c-type synthase), is a 268-amino-acid mitochondrial inner membrane protein belonging to the cytochrome c-type heme lyase family. It contains two HRM (heme regulatory motif) repeats and facilitates covalent linkage of a heme group to an apoprotein of cytochrome c. The HCCS gene is located on the human X chromosome. Mutations cause microphthalmia syndromic type 7 (MCOPS7), also known as MIDAS syndrome or microphthalmia with linear skin defects (MLS), an X-linked male-lethal disorder resulting in eye deformation, microphthalmia, and skin defects.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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