Thermo Fisher Scientific ERAB Recombinant Rabbit Monoclonal Antibody (3O4W10)
ERAB 단백질을 인식하는 재조합 토끼 단클론 항체로, Western blot 및 ELISA에 적합합니다. 인간, 마우스, 랫트 시료에 반응하며, 미토콘드리아 단백질 검출에 유용합니다. 고순도 친화 크로마토그래피 정제 및 안정한 PBS 완충액 형태로 제공됩니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| ELISA | 1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 3O4W10 |
| Immunogen | A synthetic peptide corresponding to amino acids 162–261 of human ERAB/HSD17B10 (Q99714) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.4 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 0.05% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2911780 |
Product Specific Information
- Positive test controls: 293T, HepG2, U-87MG, Mouse liver, Mouse kidney, Mouse heart, Rat liver, Rat kidney, Rat heart
- Target localization: Mitochondrion
Immunogen sequence:
QVGQAAYSAS KGGIVGMTLP IARDLAPIGI RVMTIAPGLF GTPLLTSLPE KVCNFLASQV PFPSRLGDPA EYAHLVQAII ENPFLNGEVI RLDGAIRMQP
Target Information
This gene encodes 3-hydroxyacyl-CoA dehydrogenase type II, a member of the short-chain dehydrogenase/reductase superfamily. The gene product is a mitochondrial protein that catalyzes the oxidation of various fatty acids, alcohols, and steroids. It has been implicated in Alzheimer’s disease development, and mutations cause 2-methyl-3-hydroxybutyryl-CoA dehydrogenase deficiency (MHBD). Several alternatively spliced transcript variants exist, with two full-length forms identified.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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