Thermo Fisher Scientific ERAB Recombinant Rabbit Monoclonal Antibody (3O4W10)

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:1,000

-

ELISA (ELISA)

1 µg/mL

-

Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Expression System

HEK293 cells

Class

Recombinant Monoclonal

Type

Antibody

Clone

3O4W10

Immunogen

A synthetic peptide corresponding to a sequence within amino acids 162-261 of human ERAB/HSD17B10 (Q99714). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:ERAB,uniProtId:Q99714-1,ncbiNodeId:9606,antigenRange:162-261,antigenLength:261,antigenImageFileName:MA5-42639_ERAB_Q99714-1_Rabbit.svg,antigenImageFileNamePDP:MA5-42639_ERAB_Q99714-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.4 mg/mL

Purification

Affinity Chromatography

Storage buffer

PBS, pH 7.3, with 0.05% BSA, 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2911780

Product Specific Information

Positive test controls include: 293T, HepG2, U-87MG, Mouse liver, Mouse kidney, Mouse heart, Rat liver, Rat kidney, Rat heart. The target is usually found in the following locations: Mitochondrion.

Immunogen sequence: QVGQAAYSAS KGGIVGMTLP IARDLAPIGI RVMTIAPGLF GTPLLTSLPE KVCNFLASQV PFPSRLGDPA EYAHLVQAII ENPFLNGEVI RLDGAIRMQP

Target Information

This gene encodes 3-hydroxyacyl-CoA dehydrogenase type II, a member of the short-chain dehydrogenase/reductase superfamily. The gene product is a mitochondrial protein that catalyzes the oxidation of a wide variety of fatty acids, alcohols, and steroids. The protein has been implicated in the development of Alzheimer`s disease, and mutations in the gene are the cause of 2-methyl-3-hydroxybutyryl-CoA dehydrogenase deficiency (MHBD). Several alternatively spliced transcript variants have been identified, but the full-length nature of only two transcript variants has been determined.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.