Thermo Fisher Scientific MEK1/MEK2 Recombinant Rabbit Monoclonal Antibody (ARC0292)
Thermo Fisher의 MEK1/MEK2 재조합 토끼 단클론 항체(ARC0292)는 인간, 마우스, 랫트 시료에서 반응하며 Western blot과 ELISA에 적합합니다. HEK293 세포에서 발현된 고순도 항체로, PBS/glycerol 버퍼에 보관되며 세포 성장 및 분화 관련 MAP kinase 연구에 활용됩니다.
- 판매단위
- pk
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Applications
Western Blot (WB)
- Tested Dilution: 1:5,000–1:30,000
ELISA
- Tested Dilution: 1 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | ARC0292 |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 1–360 of human MEK1/MEK2 (Q02750) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol, 0.05% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2898041 |
Product Specific Information
- Positive Samples: HeLa, HepG2, Jurkat, Mouse brain
- Immunogen sequence:
MPKKKPTPIQLNPAPDGSAVNGTSSAETNLEALQKKLEELELDEQQRKRLEAFLTQKQKVGELKDDDFEKISELGAGNGGVVFKVSHKPSGLVMARKLIHLEIKPAIRNQI IRELQVLHECNSPYIVGFYGAFYSDGEISICMEHMDGGSLDQVLKKAGR IPEQILGKVSIAVIKGLTYLREKHKIMHRDVKPSNILVNSRGEIKLCDFGVSGQLIDSMA NSFVGTRSYMSPERLQGTHYSVQSDIWSMGLSLVEMAVGRYPIPPPDAKELELMFGCQVEGDAAETPPRPRTPGRPLSSYGMDSRPPMAIFELLDYIVNEPPPKLPSGVFSLEFQDFVNKCLIKNPAERADLKQLMVHAF
Target Information
MEK1 (MAP Kinase Kinase, also known as MKK) is an integral component of the MAP kinase cascade that regulates cell growth and differentiation (Ahn, 1993; Chong et al., 2003). In brain, this pathway also plays a key role in synaptic signaling (Adams and Sweatt, 2002). Activated MEK1 acts as a dual specificity kinase phosphorylating both threonine and tyrosine residues on MAP kinase (Kyriakis et al., 1991; Seger et al., 1991; Crews et al., 1992).
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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