Thermo Fisher Scientific DRD3 Recombinant Rabbit Monoclonal Antibody (ARC1041)
DRD3 단백질을 인식하는 재조합 토끼 단클론 항체로, Western blot과 ELISA에 적합합니다. 인간, 마우스, 랫트 시료에 반응하며, 고순도의 Affinity chromatography로 정제되었습니다. PBS/glycerol buffer에 보관되며, 연구용으로만 사용 가능합니다.
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Thermo Fisher Scientific DRD3 Recombinant Rabbit Monoclonal Antibody (ARC1041)
Applications and Tested Dilution
- Western Blot (WB): 1:500–1:1,000
- ELISA: 1 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | ARC1041 |
| Immunogen | A synthetic peptide corresponding to amino acids 1–100 of human Dopamine Receptor D3 (DRD3) (UniProt ID: P35462) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.33 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol, 0.05% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2898037 |
Product Specific Information
- Positive Samples: HeLa, C6, SH-SY5Y, U-251MG, Mouse brain
- Immunogen Sequence:
MASLSQLSGH LNYTCGAENS TGASQARPHA YYALSYCALI LAIVFGNGLV CMAVLKERAL QTTTNYLVVS LAVADLLVAT LVMPWVVYLE VTGGVWNFSR
Target Information
This gene encodes the D3 subtype of the five (D1–D5) dopamine receptors. The activity of the D3 receptor is mediated by G proteins that inhibit adenylyl cyclase. It is localized in limbic areas of the brain associated with cognitive, emotional, and endocrine functions. Genetic variation may be linked to susceptibility to hereditary essential tremor 1. Alternative splicing results in transcript variants encoding different isoforms, some of which may undergo nonsense-mediated decay (NMD).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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