Thermo Fisher Scientific MLNR Polyclonal Antibody
Human, Mouse, Rat에서 반응하는 Rabbit Polyclonal Antibody로, MLNR 단백질의 367-412번 아미노산 서열을 기반으로 제작됨. Western Blot에 적합하며 항원 친화 크로마토그래피로 고순도 정제됨. PBS와 50% glycerol buffer에 보관하며 연구용으로만 사용 가능.
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Thermo Fisher Scientific MLNR Polyclonal Antibody
Applications
- Western Blot (WB)
Tested Dilution: 1:500–1:1,000
Publications: - [References not available]
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to amino acids 367–412 of Human MLNR |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2719248 |
Product Specific Information
The antibody was affinity-purified from rabbit antiserum by affinity chromatography using an epitope-specific immunogen, and the purity is >95% (by SDS-PAGE).
Target Information
Motilin is a widely conserved 22 amino acid peptide hormone secreted from enterochromaffin cells of the gastrointestinal tract. It potentiates intestinal motility by inducing contractions of the duodenum and binding to surface receptors designated GPR38 (G-protein coupled receptor 38). These motilin receptors are predominantly expressed in stomach, thyroid, and bone marrow, and are related to other G-protein coupled receptors located in the pituitary and hypothalamus, which mediate signaling for growth hormone secretagogues.
The gene encoding GPR38 is alternately spliced at the carboxy terminus to generate two related proteins, GPR38-A and GPR38-B. GPR38-A contains seven transmembrane domains, while GPR38-B is predicted to contain five. Consistent with other G-protein coupled receptors, GPR38 activates phospholipase C signal transduction pathways and induces intracellular calcium mobilization after motilin binding.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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