
Thermo Fisher Scientific TAGAP Polyclonal Antibody
TAGAP 단백질을 표적으로 하는 Thermo Fisher Scientific의 토끼 폴리클로날 항체. Western blot 등 다양한 응용에 적합하며, 높은 순도(>95%)로 정제됨. 인간, 마우스, 랫트 반응성. 장기 보관 시 -20°C에서 안정적.
- 카탈로그번호
- PA575939
- 판매단위
- pk
카탈로그
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to amino acids 186–231 of Human TAGAP |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2719667 |
Product Specific Information
The antibody was affinity-purified from rabbit antiserum by affinity chromatography using an epitope-specific immunogen. The purity is >95% (by SDS-PAGE).
Target Information
TAGAP (T-cell activation Rho GTPase-activating protein) is a 731 amino acid protein containing one Rho-GAP domain and exists as four alternatively spliced isoforms. TAGAP may function as a GTPase-activating protein and play important roles during T-cell activation.
The TAGAP gene spans approximately 10,685 bases and maps to human chromosome 6q25.3. Chromosome 6, comprising about 6% of the human genome, contains ~1,200 genes within 170 million base pairs. Deletion of part of the q arm of chromosome 6 is linked to early-onset intestinal cancer, suggesting a cancer susceptibility locus.
Chromosome 6 is also associated with various diseases, including porphyria cutanea tarda (via the HFE gene), Parkinson’s disease (PARK2 gene), and several metabolic and genetic disorders such as Stickler syndrome, hydroxylase deficiency, and maple syrup urine disease. A bipolar disorder susceptibility locus has also been identified on the q arm of chromosome 6.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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