Thermo Fisher Scientific TRAPPC5 Polyclonal Antibody
TRAPPC5 단백질을 인식하는 토끼 폴리클로날 항체로, Western blot에서 검증됨. 인간, 마우스, 랫트 반응성. 항원 친화 크로마토그래피로 정제되었으며, PBS와 글리세롤 용액 형태로 제공. 단백질 수송 및 소포체-골지체 이동 연구에 적합.
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Applications
- Western Blot (WB): 1:500–1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to amino acids 68–113 of Human TRAPPC5 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2719668 |
Product Specific Information
The antibody was affinity-purified from rabbit antiserum by affinity chromatography using an epitope-specific immunogen. The purity is greater than 95% as determined by SDS-PAGE.
Target Information
TRAPPC5 (trafficking protein particle complex 5), also known as TRS31, is a 181 amino acid protein belonging to the TRAPP (transport protein particle) small subunits family and the BET3 subfamily.
Encoded by a gene that maps to human chromosome 19p13.2, TRAPPC5 is part of the multisubunit TRAPP tethering complex, which acts as a GTP exchange factor.
Evolutionarily conserved, TRAPPC5 plays a role in protein binding, vesicle-mediated transport, and nucleotide exchange stimulation. It also functions as a guanine nucleotide exchange factor (GEF) both in vitro and in vivo.
Localizing to the Golgi apparatus, TRAPPC5 is essential for endoplasmic reticulum (ER)-to-Golgi and intra-Golgi vesicle trafficking in yeast, as well as additional transport events in mammals, such as post-Golgi trafficking.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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