Thermo Fisher Scientific AMPD1 Polyclonal Antibody
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카탈로그 번호 | CAS 번호 | 설명 | 상태 | 단위 | 판매가 | 할인가 | 가격(VAT포함) | 수량 / 장바구니 / 찜 |
PA523172 | - | Thermo Fisher Scientific PA523172 AMPD1 Polyclonal Antibody 100 ug pk | 재고문의 | pk | 691,000원 | - | 760,100원 |
다른 상품 둘러보기
Applications
Tested Dilution
Publications
Western Blot (WB)
0.5-2 µg/mL
Immunohistochemistry (Paraffin) (IHC (P))
10 µg/mL
Product Specifications
Species Reactivity
Bovine, Dog, Human, Marsupial, Mouse, Non-human primate, Rat
Host/Isotype
Rabbit / IgG
Class
Polyclonal
Type
Antibody
Immunogen
A portion of amino acids 140-190 of human AMPDA1 if (typeof window.$mangular === undefined
|| !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{
targetFamily:
AMPD1,
uniProtId:
P23109-1,
ncbiNodeId:
9606,
antigenRange:
140-190,
antigenLength:
747,
antigenImageFileName:
PA5-23172_AMPD1_P23109-1_Rabbit.svg,
antigenImageFileNamePDP:
PA5-23172_AMPD1_P23109-1_Rabbit_PDP.jpeg,
sortOrder:
1}\]
; $mangular.isB2BCMGT = false
; $mangular.isEpitopesModalImageMultiSizeEnabled = true
;
View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}
Conjugate
Unconjugated Unconjugated Unconjugated
Form
Liquid
Concentration
1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS
Contains
0.05% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2540698
Target Information
AMP deaminase (AMPD) is an allosteric enzyme involved in the regulation of adenosine metabolism. It catalyzes a central reaction in purine nucleotide biosynthesis where AMP is deaminated to IMP, liberating ammonia. There are three functional isoforms of AMPD. AMPD1 (E.C. No 3.5.4.6.) is the skeletal muscle-specific isoform M located in type II muscle fibers, neuromuscular junctions and in capillaries. This protein is the predominant member of AMPD multi-gene family and is considered as the sensor of the cell`s changing energy requirements. AMPD1 deficiency causes irregular muscle metabolism due to lower rate of ATP degradation, phosphocreatine hydrolysis and accumulation of lactic acid. Mutated AMPD1 expression has been detected in neuromuscular disorders, exercise-induced skeletal muscle myopathies and congestive heart failures due to coronary artery diseases.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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