Thermo Fisher Scientific PABPN1 Recombinant Rabbit Monoclonal Antibody (6C3)
PABPN1 단백질을 인식하는 재조합 토끼 단클론 항체로, Western blot, IHC, ICC/IF, FACS 등 다양한 응용에 적합합니다. HEK293 세포에서 발현되었으며, 고순도의 친화 크로마토그래피 정제 제품입니다. 연구용으로만 사용 가능합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:5,000 |
| Immunohistochemistry (Paraffin) (IHC-P) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:20–1:200 |
| Flow Cytometry (Flow) | 1:20–1:200 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 6C3 |
| Immunogen | A synthesized peptide derived from human PABPN1 (aa 16–28) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.19 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol, 150 mM NaCl |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C or -80°C if preferred |
| Shipping Conditions | Wet ice |
| RRID | AB_2898277 |
Product Specific Information
This antibody has been tested in direct-ELISA.
Target Information
This gene encodes an abundant nuclear protein that binds with high affinity to nascent poly(A) tails. The protein is required for progressive and efficient polymerization of poly(A) tails at the 3′ ends of eukaryotic transcripts and controls the size of the poly(A) tail to about 250 nt. At steady state, this protein is localized in the nucleus, whereas a different poly(A) binding protein is localized in the cytoplasm.
Expansion of the GCG trinucleotide repeat from the normal 6 copies to 8–13 copies leads to autosomal dominant oculopharyngeal muscular dystrophy (OPMD). Related pseudogenes have been identified on chromosomes 19 and X. Read-through transcription also exists between this gene and the neighboring upstream BCL2-like 2 (BCL2L2) gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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