Thermo Fisher Scientific DKK1 Recombinant Rabbit Monoclonal Antibody (1D12)
인간 DKK1 단백질을 인식하는 재조합 토끼 단클론 항체로, Western blot 등 다양한 응용에 적합함. HEK293 세포에서 발현되었으며, 고순도의 액상 형태로 제공됨. Wnt/β-catenin 신호 억제 연구에 유용함.
- 판매단위
- pk
카탈로그
1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific DKK1 Recombinant Rabbit Monoclonal Antibody (1D12)
Applications
- Western Blot (WB): 1:500–1:5,000
- Tested in direct-ELISA
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 1D12 |
| Immunogen | A synthesized peptide derived from human DKK1 (UniProt ID: O94907-1, antigen range: 246–260) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.2 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol, 150 mM NaCl |
| Contains | 0.02% sodium azide |
| Storage Conditions | −20°C or −80°C if preferred |
| Shipping Conditions | Wet ice |
| RRID | AB_2898278 |
Product Specific Information
This antibody has been tested in direct-ELISA.
Target Information
DKK-1 is a member of the DKK protein family, which includes DKK-2, DKK-3, and DKK-4. It was originally identified as a Xenopus head-forming molecule that acts as an antagonist for Wnt signaling. DKK-1 and DKK-4 regulate the Wnt/β-catenin signaling pathway by forming inhibitory complexes with LRP5 and LRP6, key co-receptors in this system. By inhibiting Wnt/β-catenin signaling, DKK-1 supports anterior development. Mice lacking DKK-1 expression fail to form heads and die during embryogenesis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
Thermo Fisher Scientific 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.