Thermo Fisher Scientific GABRA5 Recombinant Rabbit Monoclonal Antibody (5C11)
GABRA5 단백질을 인식하는 재조합 토끼 단클론 항체로, Western blot 및 IHC(P)에서 검증됨. 고순도 친화 크로마토그래피 정제. 인간 시료에 반응하며, PBS/glycerol 완충액에 보관. 연구용으로만 사용 가능.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:5,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 5C11 |
| Immunogen | A synthesized peptide derived from human GABA A Receptor alpha 5 (target family: GABRA5, UniProt ID: P31644-1, antigen range: 32–186, antigen length: 462) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.75 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol, 150 mM NaCl |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C or -80°C if preferred |
| Shipping Conditions | Wet ice |
| RRID | AB_2898275 |
Product Specific Information
This antibody has been tested in direct-ELISA.
Target Information
GABRA5 is a component of the GABA system, a major inhibitory neurotransmitter mechanism in the mammalian brain. It acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. At least 16 distinct subunits of GABA-A receptors have been identified. Transcript variants utilizing three different alternative non-coding first exons have been described.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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