Thermo Fisher Scientific ACVRL1 Recombinant Rabbit Monoclonal Antibody (8B6)
ACVRL1 단백질을 인식하는 토끼 유래 재조합 단클론 항체. Western blot과 IHC(P)에서 사용 가능. HEK293 세포에서 발현되며, 고순도의 Affinity chromatography로 정제. 인체, 마우스, 랫트 반응성. 연구용 전용.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:5,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 8B6 |
| Immunogen | A synthesized peptide derived from human ACVRL1 (aa 489–503) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol, 150 mM NaCl |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C or -80°C if preferred |
| Shipping Conditions | Wet ice |
| RRID | AB_2898272 |
Product Specific Information
This antibody has been tested in direct-ELISA.
Target Information
Activin A receptor type II-like 1 (ACVRL1) is a type I cell-surface receptor for the TGF-beta superfamily of ligands. Similar to other type I receptors, ACVRL1 contains a conserved serine-threonine kinase subdomain, a glycine- and serine-rich GS domain preceding the kinase domain, and a short C-terminal tail. Mutations in ACVRL1 are associated with hemorrhagic telangiectasia type 2 and have also been linked to Fibrodysplasia Ossificans Progressiva (FOP), a rare genetic disorder characterized by heterotopic bone formation in soft tissues.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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