Thermo Fisher Scientific PCDH15 Monoclonal Antibody (OTI7F10), TrueMAB
PCDH15 단백질을 인식하는 마우스 단일클론 항체로, Western blot에 최적화됨. 인간, 생쥐, 랫트 반응성. 무보존제, 동결건조 형태로 제공되며, 재구성 시 1 mg/mL 농도로 사용 가능. 세포 접착 및 청각 관련 연구에 적합.
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Applications
- Western Blot (WB)
Tested Dilution: 1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI7F10 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 160–400 of human PCDH15 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using this carrier-free antibody, perform an additional desalting step (recommended: Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
PCDH15 belongs to the cadherin superfamily, encoding integral membrane proteins that mediate calcium-dependent cell-cell adhesion.
It contains a signal peptide, 11 extracellular calcium-binding domains, a transmembrane domain, and a unique cytoplasmic domain.
PCDH15 plays a crucial role in maintaining normal retinal and cochlear function. Mutations are associated with hearing loss and Usher syndrome type 1F (USH1F) on chromosome 10.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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