Thermo Fisher Scientific Relaxin 1 Polyclonal Antibody

Applications

Western Blot (WB)

• Tested Dilution: 0.1–0.5 µg/mL

Immunohistochemistry (Paraffin) (IHC (P))

• Tested Dilution: 0.5–1 µg/mL

Product Specifications

Product Specific Information

Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 µg/mL.

Target Information

Relaxins are known endocrine and autocrine/paracrine hormones belonging to the insulin gene superfamily. In humans, three non-allelic relaxin genes exist: RLN1, RLN2, and RLN3.
RLN1 and RLN2 share high sequence homology. The encoded protein is synthesized as a single-chain polypeptide, but the active form consists of an A chain and a B chain linked by disulfide bonds. Relaxin is produced by the ovary and affects the reproductive system by ripening the cervix, elongating the pubic symphysis, and inhibiting uterine contraction.
Additional roles may include enhancing sperm motility, regulating blood pressure, controlling heart rate, and releasing oxytocin and vasopressin.
This gene has multiple polyadenylation sites and alternatively spliced transcript variants whose full-length nature is not yet known.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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