Thermo Fisher Scientific ENPP4 Polyclonal Antibody
Thermo Fisher Scientific의 ENPP4 Polyclonal Antibody는 인간 ENPP4 단백질을 검출하는 토끼 IgG 기반 항체입니다. Western blot과 IHC(P) 실험에 적합하며, 항원 친화 크로마토그래피로 정제되었습니다. 연구용으로만 사용 가능합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:2,000
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:25–1:100
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to a region derived from internal residues of human ectonucleotide pyrophosphatase/phosphodiesterase 4 (putative) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.5 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 40% glycerol |
| Contains | 0.05% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2636107 |
Product Specific Information
The antibody detects endogenous levels of total ENPP4 protein.
Target Information
NPP4, also known as ENPP4 (ectonucleotide pyrophosphatase/phosphodiesterase family member 4), is a 453 amino acid single-pass type I membrane protein belonging to the nucleotide pyrophosphatase/phosphodiesterase family.
The gene encoding NPP4 spans approximately 16,736 bases and maps to human chromosome 6p21.1. Chromosome 6 comprises about 6% of the human genome, containing roughly 1,200 genes within 170 million base pairs.
Deletion of a portion of the q arm of chromosome 6 is associated with early onset intestinal cancer, suggesting a cancer susceptibility locus. Porphyria cutanea tarda is linked to chromosome 6 through the HFE gene, and Stickler syndrome, 21-hydroxylase deficiency, and maple syrup urine disease are also associated with genes on this chromosome.
Notably, the PARK2 gene (related to Parkinson’s disease) and genes encoding major histocompatibility complex proteins are located on chromosome 6. A bipolar disorder susceptibility locus has also been identified on the q arm of chromosome 6.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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