Thermo Fisher Scientific ENPP4 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:2,000

-

Immunohistochemistry (Paraffin) (IHC (P))

1:25-1:100

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Synthetic peptide corresponding to a region derived from internal residues of human ectonucleotide pyrophosphatase/phosphodiesterase 4 (putative)

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1.5 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.4, with 40% glycerol

Contains

0.05% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice

RRID

AB_2636107

Product Specific Information

The antibody detects endogenous levels of total ENPP4 protein.

Target Information

NPP4, also known as ENPP4 (ectonucleotide pyrophosphatase/phosphodiesterase family member 4), is a 453 amino acid single-pass type I membrane protein that belongs to the nucleotide pyrophosphatase/phosphodiesterase family. The gene that encodes NPP4 consists of approximately 16, 736 bases and maps to human chromosome 6p21.1. Making up nearly 6% of the human genome, chromosome 6 contains around 1, 200 genes within 170 million base pairs of sequence. Deletion of a portion of the q arm of chromosome 6 is associated with early onset intestinal cancer suggesting the presence of a cancer susceptibility locus. Porphyria cutanea tarda is associated with chromosome 6 through the HFE gene, and Stickler syndrome, 21-hydroxylase deficiency and maple syrup urine disease are also associated with genes on chromosome 6. Notably, the PARK2 gene, which is associated with Parkinson`s disease, and the genes encoding the major histocompatibility complex proteins are also located on chromosome 6. A bipolar disorder susceptibility locus has been identified on the q arm of chromosome 6.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.