Thermo Fisher Scientific SPINLW1 Polyclonal Antibody
Rabbit polyclonal antibody detecting endogenous EPPIN protein. Suitable for Western blot and IHC applications. Reacts with human and mouse samples. Purified by antigen affinity chromatography. Supplied in PBS with glycerol for stable storage at -20°C.
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Thermo Fisher Scientific SPINLW1 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:25–1:100 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to a region derived from internal residues of human epididymal peptidase inhibitor |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 2.4 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 40% glycerol |
| Contains | 0.05% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2636108 |
Product Specific Information
This antibody detects endogenous levels of total EPPIN protein.
Target Information
Eppin (epididymal protease inhibitor) belongs to the WFDC family and the telomeric cluster. The gene encoding Eppin is localized to chromosome 20q12–q13 and expresses three mRNAs encoding two isoforms of a cystine-rich protein containing Kunitz-type and WAP-type protease inhibitor consensus sequences.
In mice, the gene lies in a cluster of Eppin-like genes on chromosome 2. After ejaculation, Eppin binds to semenogelin in seminal plasma and on human spermatozoa. The Eppin–Semenogelin complex provides antimicrobial activity and supports sperm preparation and survival in the female reproductive tract.
Eppin is a secreted protein expressed in the epididymis and testis.
Usage Notice
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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