Thermo Fisher Scientific FAM13B Polyclonal Antibody
Rabbit polyclonal antibody recognizing endogenous FAM13B protein in human and mouse samples. Suitable for IHC (Paraffin) applications with dilution range 1:25–1:100. Purified by antigen affinity chromatography and supplied as liquid form in PBS with gl...
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Applications
- Immunohistochemistry (Paraffin) (IHC (P)): 1:25–1:100
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to a region derived from internal residues of human family with sequence similarity 13, member B |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.3 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 40% glycerol |
| Contains | 0.05% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2636111 |
Product Specific Information
The antibody detects endogenous levels of total FAM13B protein.
Target Information
FAM13B is a 915 amino acid protein encoded by a gene located on human chromosome 5. Chromosome 5 contains approximately 181 million base pairs and around 1,000 genes, accounting for about 6% of human genomic DNA.
It is associated with several genetic conditions:
- Cockayne syndrome (via ERCC8 gene)
- Familial adenomatous polyposis (via APC tumor suppressor gene)
- Treacher Collins syndrome (via TCOF1 gene mutations)
- Cri du chat syndrome (caused by deletion of the p arm of chromosome 5)
Deletion of 5q or chromosome 5 is commonly observed in therapy-related acute myelogenous leukemia and myelodysplastic syndrome.
For Research Use Only. Not for use in diagnostic procedures or resale without express authorization.
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