Thermo Fisher Scientific DSC1 Polyclonal Antibody
Rabbit polyclonal antibody against human DSC1 protein. Validated for IHC (paraffin) applications with dilution 1:50–1:200. Detects endogenous DSC1 involved in epidermal adhesion. Supplied as liquid, 2.8 mg/mL, in PBS with 40% glycerol. For research use...
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to residues near the C-terminal of human desmocollin 1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 2.8 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 40% glycerol |
| Contains | 0.05% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2636104 |
Product Specific Information
The antibody detects endogenous levels of total DSC1 protein.
Target Information
Desmocollin 1 (DSC1) is a desmosomal cadherin expressed in the upper epidermis, where strong adhesion is required.
DSC1 is a type I membrane protein essential for epidermal adhesion and barrier maintenance, contributing to epidermal differentiation.
The DSC1 gene comprises 17 exons spanning approximately 33 kb on chromosome 18q12.1.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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