Thermo Fisher Scientific DFNA5 Monoclonal Antibody (A1H2)
DFNA5 단백질을 인식하는 Thermo Fisher Scientific의 Mouse Monoclonal Antibody (A1H2). Western blot, ICC/IF, Flow cytometry에 최적화. Human 시료 반응성, Protein G 정제, 고농도(2 mg/mL) 액상 형태로 안정적 보관 가능.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunocytochemistry (ICC/IF) | 1:50–1:100 |
| Flow Cytometry (Flow) | 1:50–1:100 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | A1H2 |
| Immunogen | Recombinant protein within Human DFNA5 (aa 34–214) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 2 mg/mL |
| Purification | Protein G |
| Storage Buffer | PBS, pH 7.4, with 0.2% BSA, 50% glycerol |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2897723 |
Product Specific Information
Positive controls: Hela cell lysates, HepG2 cell lysates, A431, SiHa, SH-SY5Y.
Target Information
DFNA5 (deafness, autosomal dominant 5), also known as ICERE-1, is a 496 amino acid protein expressed in cochlea tissue as well as placenta, brain, heart, liver, lung, and pancreas. It exists as two alternatively spliced isoforms (short and long). Mutations in DFNA5 cause non-syndromic sensorineural deafness autosomal dominant type 5 (DFNA5), a form of hearing loss due to damage in auditory structures.
The DFNA5 gene is located on human chromosome 7, which contains over 1,000 genes and represents nearly 5% of the human genome. Defects in genes on chromosome 7 are associated with disorders such as Osteogenesis imperfecta, Williams-Beuren syndrome, Pendred syndrome, Lissencephaly, Citrullinemia, and Shwachman-Diamond syndrome.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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