Thermo Fisher Scientific APOE (R136S Mutant) Polyclonal Antibody
APOE (R136S Mutant) 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot 및 Immunocytochemistry에 적합합니다. 항원 친화 크로마토그래피로 정제되었으며, PBS 기반 용액에 BSA와 glycerol이 포함되어 안정성이 우수합니다. 연구용 전용 제품입니다.
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Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:500–1:3,000 | - |
| Immunocytochemistry (ICC/IF) | Assay-dependent | - |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Carrier-protein conjugated synthetic peptide encompassing a sequence within the center region of human Apolipoprotein E (R136S Mutant). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.15 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7, with 1% BSA, 20% glycerol |
| Contains | 0.025% ProClin 300 |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Wet ice |
| RRID | AB_2913093 |
Product Specific Information
Store as concentrated solution. Centrifuge briefly prior to opening vial.
For short-term storage (1–2 weeks), store at 4°C.
For long-term storage, aliquot and store at -20°C or below.
Avoid multiple freeze-thaw cycles.
Target Information
The protein encoded by this gene is a major apoprotein of the chylomicron. It binds to a specific liver and peripheral cell receptor, and is essential for the normal catabolism of triglyceride-rich lipoprotein constituents.
This gene maps to chromosome 19 in a cluster with the related apolipoprotein C1 and C2 genes.
Mutations in this gene result in familial dysbetalipoproteinemia (type III hyperlipoproteinemia, HLP III), characterized by increased plasma cholesterol and triglycerides due to impaired clearance of chylomicron and VLDL remnants.
[provided by RefSeq, Jun 2016]
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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