Thermo Fisher Scientific DTNA Monoclonal Antibody (OTI1A2), TrueMAB
DTNA 단백질을 인식하는 Mouse IgG2a 단일클론 항체로, Western blot, ICC/IF, Flow Cytometry에 적합합니다. 인간 DTNA 전장 재조합 단백질을 면역원으로 제작되었으며, carrier-free로 제공되어 다양한 접합 실험에 활용 가능합니다.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Immunocytochemistry (ICC/IF) | 1:100 |
| Flow Cytometry (Flow) | 1:100 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1A2 |
| Immunogen | Full length human recombinant protein of human DTNA produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Additional Formats
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using this carrier-free antibody, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
The DTNA protein belongs to the dystrobrevin subfamily of the dystrophin family and is a component of the dystrophin-associated protein complex (DPC). The DPC includes dystrophin and several integral and peripheral membrane proteins such as dystroglycans, sarcoglycans, syntrophins, and alpha- and beta-dystrobrevins.
This complex localizes to the sarcolemma, and its disruption is associated with various forms of muscular dystrophy. Mutations in the DTNA gene are linked to left ventricular noncompaction with congenital heart defects. Multiple alternatively spliced transcript variants encoding different isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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