Thermo Fisher Scientific ATF4 Polyclonal Antibody

Applications

Western Blot (WB)

• Tested Dilution: 0.1–0.5 µg/mL

Immunohistochemistry (Paraffin) (IHC (P))

• Tested Dilution: 0.5–1 µg/mL

Product Specifications

Product Specific Information

Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 µg/mL.

Target Information

The ATF4 gene encodes a transcription factor originally identified as a mammalian DNA-binding protein that interacts with the tax-responsive enhancer element in the LTR of HTLV-1. It is also known as cAMP-response element-binding protein 2 (CREB-2).
ATF4 belongs to a family of DNA-binding proteins including AP-1, CREBs, and CREB-like proteins. These transcription factors share a leucine zipper region for protein-protein interactions and a basic amino acid stretch functioning as a DNA-binding domain.
Two alternative transcripts encoding the same protein have been described. Two pseudogenes are located on the X chromosome at q28 within a large inverted duplication region.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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