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Thermo Fisher Scientific Lamin A/C (R482W) Monoclonal Antibody (5H8-B4)
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Lamin A/C R482W 변이체를 특이적으로 인식하는 mouse monoclonal antibody. Western blot, ICC/IF, IP 등에 사용 가능. Protein G로 정제된 액상형 제품으로, 1 mg/mL 농도. 단기 4°C, 장기 -20°C 보관 권장.
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마지막 업데이트 2025. 08. 01. 오후 08:54
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Thermo Fisher Scientific MA518063 Lamin A/C (R482W) Monoclonal Antibody (5H8-B4) 100 ul pk판매 단위 pk ·
재고 확인 필요
783,000원VAT 포함 861,300원
Thermo Fisher Scientific · Thermo Fisher Scientific Lamin A/C (R482W) Monoclonal Antibody (5H8-B4)
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:32,000 |
| Immunocytochemistry (ICC/IF) | Assay-dependent |
| Immunoprecipitation (IP) | Assay-dependent |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 5H8-B4 |
| Immunogen | Lamin A Ig-fold; human (sequence: 430–545, 6xHis-tagged fusion protein) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein G |
| Storage Buffer | PBS |
| Contains | 0.1% sodium azide |
| Storage Conditions | Store at 4°C short term; for long-term storage, store at -20°C, avoiding freeze/thaw cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2539446 |
Product Specific Information
This antibody recognizes the FPLD-associated lamin A/C mutant strain R482W.
Target Information
Lamins are intermediate filament proteins forming a matrix on the inner surface of the nuclear envelope. They exist in several isoforms (A, B, and C), with Lamins A and C being splice variants of the LMNA gene.
Mutations in LMNA are associated with multiple disorders, including:
- Emery-Dreifuss muscular dystrophy
- Dunnigan-type familial partial lipodystrophy (FPLD)
- Limb-girdle muscular dystrophy (LGMD1B)
- Dilated cardiomyopathy (CMD1A)
- Axonal neuropathy (Charcot-Marie-Tooth disease; CMT2B1)
- Mandibuloacral dysplasia (MAD)
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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