Thermo Fisher Scientific alpha Galactosidase Polyclonal Antibody
Thermo Fisher Scientific의 알파 갈락토시다제 폴리클로날 항체로, 인간 시료에 반응하며 WB, IHC, ICC/IF에 사용 가능. 항원 친화 크로마토그래피로 정제된 고순도 항체로, 1 mg/mL 농도의 액상 형태. 연구용으로 Fabry 질환 관련 연구에 적합.
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- PA5119890
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:600 |
| Immunocytochemistry (ICC/IF) | 1:200 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein within human Galactosidase alpha (aa 81–280) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 40% glycerol, 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2913462 |
Product Specific Information
- Positive Control: 293T cell lysate, MCF-7 cell lysate, Hela, human breast tissue, human endometrium tissue, human kidney tissue
- Subcellular Location: Lysosome
Target Information
This gene encodes a homodimeric glycoprotein that hydrolyzes the terminal alpha-galactosyl moieties from glycolipids and glycoproteins.
The enzyme predominantly hydrolyzes ceramide trihexoside and can catalyze the hydrolysis of melibiose into galactose and glucose.
Various mutations in this gene affect the synthesis, processing, and stability of this enzyme, leading to Fabry disease, a lysosomal storage disorder caused by the failure to catabolize alpha-D-galactosyl glycolipid moieties.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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