Thermo Fisher Scientific IFNGR2 Polyclonal Antibody
IFNGR2 단백질을 인식하는 Rabbit Polyclonal 항체로, Human, Mouse, Rat 시료에 반응합니다. WB, IHC(P), ICC/IF에 사용 가능하며, 고순도 친화 크로마토그래피로 정제되었습니다. 세포막 및 세포질 내 IFNGR2 검출에 적합합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:600 |
| Immunocytochemistry (ICC/IF) | 1:200 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host/Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide within human IFN gamma Receptor beta (aa 288–337) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.4, with 40% glycerol, 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2913463 |
Product Specific Information
Positive Control: Jurkat cell lysate, Hela cell lysate, A431 cell lysate, human liver tissue lysate, SH-SY5Y, human stomach tissue, mouse bladder tissue, rat lung tissue.
Subcellular Location: Golgi apparatus membrane, Cell membrane, Cytoplasm, Endoplasmic reticulum membrane, Cytoplasmic vesicle membrane.
Target Information
The IFNGR2 gene encodes the non-ligand-binding beta chain of the gamma interferon receptor. The human interferon-gamma receptor is a heterodimer of IFNGR1 and IFNGR2.
Defects in IFNGR2 are associated with mendelian susceptibility to mycobacterial disease (MSMD), also known as familial disseminated atypical mycobacterial infection.
MSMD is a genetically heterogeneous disorder with autosomal recessive, autosomal dominant, or X-linked inheritance.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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