Thermo Fisher Scientific IFNGR2 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:1000

-

Immunohistochemistry (Paraffin) (IHC (P))

1:600

-

Immunocytochemistry (ICC/IF)

1:200

-

Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Synthetic peptide within human IFN gamma Receptor beta aa 288-337 if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:IFNGR2,uniProtId:P38484-1,ncbiNodeId:9606,antigenRange:288-337,antigenLength:337,antigenImageFileName:PA5-119891_IFNGR2_P38484-1_Rabbit.svg,antigenImageFileNamePDP:PA5-119891_IFNGR2_P38484-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Affinity chromatography

Storage buffer

PBS, pH 7.4, with 40% glycerol, 0.05% BSA

Contains

0.05% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2913463

Product Specific Information

Positive Control: Jurkat cell lysate, Hela cell lysate, A431 cell lysate, human liver tissue lysate, SH-SY5Y, human stomach tissue, mouse bladder tissue, rat lung tissue.

Subcellular Location: Golgi apparatus membrane, Cell membrane, Cytoplasm, Endoplasmic reticulum membrane, Cytoplasmic vesicle membrane.

Target Information

This gene (IFNGR2) encodes the non-ligand-binding beta chain of the gamma interferon receptor. Human interferon-gamma receptor is a heterodimer of IFNGR1 and IFNGR2. Defects in IFNGR2 are a cause of mendelian susceptibility to mycobacterial disease (MSMD), also known as familial disseminated atypical mycobacterial infection. MSMD is a genetically heterogeneous disease with autosomal recessive, autosomal dominant or X-linked inheritance.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.