Thermo Fisher Scientific KMT2D Recombinant Superclonal Antibody (9HCLC)

Applications

Immunocytochemistry (ICC/IF)

• Tested Dilution: 2 µg/mL

Product Specifications

Product Specific Information

This antibody is predicted to react with Monkey, Cat, and Rat.

Recombinant rabbit Superclonal™ antibodies are unique offerings from Thermo Fisher Scientific. They consist of multiple recombinant monoclonal antibodies, combining the sensitivity of polyclonal antibodies with the specificity of monoclonal antibodies, while maintaining lot-to-lot consistency. Functionally similar to polyclonal antibodies, they recognize multiple epitope sites and provide higher detection sensitivity for low-abundance targets. Each lot contains a defined mixture of light and heavy chains, eliminating biological variability.
Note: Formerly called “Recombinant polyclonal antibody”, now rebranded as “Recombinant Superclonal™ antibody”. Product and performance remain unchanged.

Target Information

KMT2D is a histone methyltransferase that methylates Lys-4 of histone H3 (H3K4me), a key marker for epigenetic transcriptional activation. It acts as a coactivator for estrogen receptors, being recruited by ESR1 to activate transcription. KMT2D is involved in chromatin organization, silencing, oocyte growth, oogenesis, and positive regulation of cell proliferation. Mutations in the KMT2D gene are associated with Kabuki syndrome (KABUK1), a congenital mental retardation syndrome.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.