Thermo Fisher Scientific Complement Factor Bb Monoclonal Antibody (10-09)
인간 Complement Factor Bb를 인식하는 마우스 단클론 항체입니다. Western blot, IHC(F), Flow cytometry, ELISA 등 다양한 응용에 사용 가능합니다. 단백질 A로 정제된 액상 형태이며, 4°C 단기 보관 및 -20°C 장기 보관이 권장됩니다. 연구용으로만 사용됩니다.
✨AI 추천 연관 상품
AI가 분석한 이 상품과 연관된 추천 상품들을 확인해보세요
연관 상품을 찾고 있습니다...
Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | Assay-dependent | - |
| Immunohistochemistry (Frozen) (IHC (F)) | Assay-dependent | - |
| Flow Cytometry (Flow) | Assay-dependent | - |
| ELISA | Assay-dependent | - |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 10-09 |
| Immunogen | Human factor B |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.05 mg/mL |
| Purification | Protein A |
| Storage Buffer | BBS |
| Contains | 0.1% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2745075 |
Product Specific Information
This antibody recognizes the Bb fragment (90 kDa) of human complement factor B, present in blood serum.
C3b associates with complement factor B, inducing a conformational change that enables complement factor D to cleave the N-terminal of complement factor B, releasing the Ba subunit and leaving the 63 kDa Bb subunit associated with C3b to form C3 convertase.
Subunit Bb is involved in the proliferation of preactivated B lymphocytes, whereas Ba inhibits lymphocyte proliferation.
Target Information
CFB (Complement Factor B) is involved in atypical hemolytic uremic syndrome type 4 (AHUS4), a genetic disorder characterized by microangiopathic hemolytic anemia, thrombocytopenia, renal failure, and absence of enterocolitis or diarrhea episodes.
Atypical forms have poorer prognosis, higher mortality, and frequent progression to end-stage renal disease.
Disease susceptibility is linked to genetic variations in complement cascade components or regulatory factors.
Mutations in these genes can modify the phenotype and influence disease development.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
🏷️Thermo Fisher Scientific 상품 둘러보기
동일 브랜드의 다른 상품들을 확인해보세요
Thermo Fisher Scientific
Thermo Fisher Scientific Complement C4c Monoclonal Antibody (10-12)
926,700원
Thermo Fisher Scientific
Thermo Fisher Scientific Complement C3c Monoclonal Antibody (10-02A)
926,700원
Thermo Fisher Scientific
Thermo Fisher Scientific Complement Factor Bb Monoclonal Antibody (10-09)
926,700원
Thermo Fisher Scientific
Thermo Fisher Scientific Complement Factor Bb Neoantigen Monoclonal Antibody (032B-22.1.X)
1,186,700원
Thermo Fisher Scientific
Thermo Fisher Scientific Phospho-MAPKAPK2 (Thr334) Recombinant Rabbit Monoclonal Antibody (MAPKAPK2T334-H2)
682,300원
배송/결제/교환/반품 안내
배송 정보
| 기본 배송비 |
| 교환/반품 배송비 |
|
|---|---|---|---|
| 착불 배송비 |
| ||
| 교환/반품 배송비 |
| ||
결제 및 환불 안내
| 결제수단 |
|
|---|---|
| 취소 |
|
| 반품 |
|
| 환급 |
|
교환 및 반품 접수
| 교환 및 반품 접수 기한 |
|
|---|---|
| 교환 및 반품 접수가 가능한 경우 |
|
| 교환 및 반품 접수가 불가능한 경우 |
|
교환 및 반품 신청
| 교환 절차 |
|
|---|---|
| 반품 절차 |
|