Thermo Fisher Scientific Complement C4c Monoclonal Antibody (10-12)
인간 Complement C4c를 인식하는 Mouse IgG1 단일클론 항체로, WB, IHC(F), Flow, ELISA 등 다양한 분석에 사용 가능. 단백질 A로 정제된 액상 형태이며, 단기 4°C, 장기 -20°C 보관. 연구용으로만 사용.
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Applications
Western Blot (WB)
- Tested Dilution: Assay-dependent
Immunohistochemistry (Frozen) (IHC (F))
- Tested Dilution: Assay-dependent
Flow Cytometry (Flow)
- Tested Dilution: Assay-dependent
ELISA
- Tested Dilution: Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 10-12 |
| Immunogen | Purified human C4c |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.15 mg/mL |
| Purification | Protein A |
| Storage Buffer | BBS |
| Contains | <0.1% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2745077 |
Product Specific Information
This antibody recognizes complement component 4c (C4c). The complement 1 complex cleaves complement 4 (C4) to form C4b and C4a. C4b levels are strictly regulated.
Target Information
C4B may be involved in systemic lupus erythematosus (SLE), a chronic, relapsing, inflammatory, and often febrile multisystemic disorder of connective tissue. It is characterized by involvement of the skin, joints, kidneys, and serosal membranes. The disease is thought to result from failure of autoimmune regulatory mechanisms. Susceptibility to SLE is associated with variations affecting the C4 gene, including copy-number variation (CNV) and polymorphisms. Individuals with fewer copies of total C4 show increased risk, while higher copy numbers are protective.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지 정보: MA5-28087_Complement_C4c_P0C0L5-1_House_mouse.svg 및 MA5-28087_Complement_C4c_P0C0L5-1_House_mouse_PDP.jpeg)
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