Thermo Fisher Scientific Phospho-PLD1 (Thr147) Polyclonal Antibody
PLD1 단백질의 Thr147 인산화 형태를 특이적으로 인식하는 폴리클로날 항체. Western blot에 적합하며, 인간, 마우스, 랫트 시료에서 반응. 1 mg/mL 액상 형태로 제공되며, -20°C에서 보관. 세포 신호전달 및 인산화 연구에 유용.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human PLD1 (Accession Q13393), corresponding to amino acid residues around phosphorylated Thr147 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Sequential chromatography |
| Storage buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C |
| Shipping conditions | Wet ice |
| RRID | AB_2816677 |
Product Specific Information
Antibody detects endogenous levels of PLD1 only when phosphorylated at Thr147.
Target Information
Phosphatidylcholine (PC)-specific phospholipases D (PLDs; EC 3.1.4.4) catalyze the hydrolysis of PC to produce phosphatidic acid and choline.
A range of agonists acting through G protein-coupled receptors and receptor tyrosine kinases stimulate this hydrolysis.
PC-specific PLD activity has been implicated in numerous cellular pathways, including signal transduction, membrane trafficking, and the regulation of mitosis (Hammond et al., 1995).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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