Thermo Fisher Scientific L1CAM Monoclonal Antibody (3B10)
인간 L1CAM/CD171 단백질을 인식하는 마우스 모노클로날 항체. Western blot 및 ELISA에 적합. PBS buffer에 보관되며 보존제가 없음. 신경계 발달 관련 연구용으로 사용.
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Applications
Western Blot (WB)
- Tested Dilution: 1–5 µg/mL
ELISA
- Tested Dilution: 0.3 ng/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 3B10 |
| Immunogen | L1CAM (NP_000416, 23–132 a.a) partial recombinant protein with GST tag (MW of GST tag alone: 26 KDa) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Sequence of this protein:
PEEYEGHHVM EPPVITEQSP RRLVVFPTDD ISLKCEASGK PEVQFRWTRD GVHFKPKEEL GVTVYQSPHS GSFTITGNNS NFAQRFQGIY RCFASNKLGT AMSHEIRLMA
Target Information
L1CAM/CD171 is an axonal glycoprotein belonging to the immunoglobulin supergene family.
The ectodomain consists of several immunoglobulin-like domains and fibronectin-like type III repeats, linked via a single transmembrane sequence to a conserved cytoplasmic domain.
This cell adhesion molecule plays an important role in nervous system development, including neuronal migration and differentiation.
Mutations in the gene cause three X-linked neurological syndromes known collectively as CRASH (corpus callosum hypoplasia, retardation, aphasia, spastic paraplegia, and hydrocephalus).
Alternative splicing of a neuron-specific exon is thought to be functionally relevant.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지 파일: H00003897-M11_CD171_L1CAM_P32004-1_House_mouse.svg, H00003897-M11_CD171_L1CAM_P32004-1_House_mouse_PDP.jpeg)
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