Thermo Fisher Scientific KRT81 Monoclonal Antibody (S3)

Applications

Tested Dilution

Publications

Western Blot (WB)

Assay-Dependent

-

Immunohistochemistry (Paraffin) (IHC (P))

3 µg/mL

-

Immunocytochemistry (ICC/IF)

10 µg/mL

-

ELISA (ELISA)

10 µg/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Mouse / IgG2b, kappa

Class

Monoclonal

Type

Antibody

Clone

S3

Immunogen

KRT81 (AAH21241, 1 a.a. approximately 202 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:KRT81,uniProtId:Q14533-1,ncbiNodeId:9606,antigenRange:1-505,antigenLength:505,antigenImageFileName:H00003887-M01J_KRT81_Q14533-1_House_mouse.svg,antigenImageFileNamePDP:H00003887-M01J_KRT81_Q14533-1_House_mouse_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

See Label

Purification

Affinity chromatography

Storage buffer

PBS, pH 7.4

Contains

no preservative

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

Product Specific Information

Sequence of this protein is as follows: MKATVIRHGE TLRRTKEEIN ELNRMIQRLT AEVENAKCQN SKLEAAVAQS EQQGEAALSD ARCKLAELEG ALQKAKQDMA CLIREYQEVM NSKLGLDIEI ATYRRLLEGE EQRLCEGIGA VNVCVSSSRG GVVCGDLCVS GSRPVTGSVC SAPCNGNVAV STGLCAPCGQ LNTTCGGGSC GVGSCGISSL GVGSCGSSCR KC

Target Information

The protein encoded by this gene is a member of the keratin gene family. As a type II hair keratin, it is a basic protein which heterodimerizes with type I keratins to form hair and nails. The type II hair keratins are clustered in a region of chromosome 12q13 and are grouped into two distinct subfamilies based on structure similarity. One subfamily, consisting of KRTHB1, KRTHB3, and KRTHB6, is highly related. The other less-related subfamily includes KRTHB2, KRTHB4, and KRTHB5. All hair keratins are expressed in the hair follicle; this hair keratin, as well as KRTHB3 and KRTHB6, is found primarily in the hair cortex. Mutations in this gene and KRTHB6 have been observed in patients with a rare dominant hair disease, monilethrix.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.