Thermo Fisher Scientific LAMA2 Monoclonal Antibody (1A7)

Applications

Tested Dilution

Publications

Western Blot (WB)

1-5 µg/mL

-

ELISA (ELISA)

10 µg/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Mouse / IgG1, kappa

Class

Monoclonal

Type

Antibody

Clone

1A7

Immunogen

LAMA2 (NP_000417, 3013 a.a. approximately 3122 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:Laminin alpha-2,uniProtId:P24043-1,ncbiNodeId:9606,antigenRange:3013-3122,antigenLength:3122,antigenImageFileName:H00003908-M02_Laminin_alpha-2_P24043-1_House_mouse.svg,antigenImageFileNamePDP:H00003908-M02_Laminin_alpha-2_P24043-1_House_mouse_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

See Label

Purification

Affinity chromatography

Storage buffer

PBS, pH 7.4

Contains

no preservative

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

Product Specific Information

Sequence of this protein is as follows: DAGVPGHLCD GQWHKVTANK IKHRIELTVD GNQVEAQSPN PASTSADTND PVFVGGFPDD LKQFGLTTSI PFRGCIRSLK LTKGTGKPLE VNFAKALELR GVQPVSCPAN

Target Information

Laminin is a non-collagenous protein of basement membranes. By rotary shadowing it has a cross-like shape, consisting of one long arm, (400 kD) and three short arms (200 kD). Antibodies to laminin localize exclusively in basement membranes. Laminin is found throughout the basement membrane, but the reaction with the antibodies to laminin is more intense in the lamina lucida, the part of the basement membrane adjacent to the cell membrane. Laminin binds to type IV collagen, a component exclusively localized in the basement membrane. Laminin has been shown to play a role in cell adhesion and attachment in vivo and in vitro.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.