Thermo Fisher Scientific POMGNT1 Polyclonal Antibody
POMGNT1 단백질을 인식하는 Rabbit Polyclonal 항체로, WB 및 ICC/IF에 적합합니다. Human, Mouse, Rat에서 반응하며, 액상 형태로 제공됩니다. Affinity chromatography로 정제되었으며, -20°C 보관이 권장됩니다.
- 카탈로그번호
- PA5100281
- 판매단위
- pk
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:2,000
Immunocytochemistry (ICC/IF)
- Tested Dilution: 1:100–1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human POMGNT1 (Accession Q8WZA1), corresponding to amino acid residues L622–T660 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C |
| Shipping conditions | Wet ice |
| RRID | AB_2815811 |
Product Specific Information
This antibody detects endogenous levels of total MGAT1.
Target Information
The POMGNT1 gene encodes protein O-mannose beta-1,2-N-acetylglucosaminyltransferase, which participates in O-mannosyl glycan synthesis. POMGnT1 is a type II membrane protein localized in the medial-Golgi that initiates the conversion of high mannose N-glycans to complex N-glycans. It acts as a glycosylation enzyme involved in the synthesis of O-mannosyl glycan, a laminin-binding ligand of alpha-dystroglycan rarely synthesized in mammals. Mutations in the POMGNT1 gene cause muscle-eye-brain disease (MEB), an autosomal recessive disorder characterized by congenital muscular dystrophy, ocular abnormalities, and lissencephaly.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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