Thermo Fisher Scientific Nebulin Polyclonal Antibody
Human, Mouse, Rat에서 반응하는 Nebulin 단백질에 대한 Rabbit Polyclonal 항체. Western blot에 적합하며, Affinity chromatography로 정제됨. PBS/glycerol buffer에 보관되며 -20°C에서 저장. 연구용 전용 제품.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human NEB (Accession P20929), corresponding to amino acid residues Y5906–T5956 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2849801 |
Product Specific Information
The immunogen sequence for PA5-100287 is KESQQMQSGK EYRKD.
Antibody detects endogenous levels of total NEB.
Target Information
Nebulin is a giant cytoskeletal protein that coexists with thick and thin filaments within skeletal muscle sarcomeres. It accounts for 3–4% of total myofibrillar protein in most vertebrates. The protein includes ~30 amino acid modules classified into 7 types and other repeats. Isoform sizes range from 600–800 kDa due to tissue-, species-, and developmental stage-specific alternative splicing. Of the 183 exons, at least 43 are alternatively spliced. Mutations in the nebulin gene are linked to recessive nemaline myopathy.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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