Thermo Fisher Scientific ACTA1/ACTA2/ACTC1 Polyclonal Antibody
ACTA1/ACTA2/ACTC1 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot에 최적화됨. 사람, 마우스, 랫트 시료 반응성. 친화 크로마토그래피로 정제된 액상 항체로, PBS/glycerol buffer에 보관. 연구용으로만 사용 가능.
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Applications
- Western Blot (WB): 1:500–1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human ACTA1 (Accession P68133), corresponding to amino acid residues M1–P34 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C |
| Shipping conditions | Wet ice |
| RRID | AB_2815832 |
Product Specific Information
This antibody detects endogenous levels of total ACTA1/A2/C1.
Target Information
The product encoded by this gene belongs to the actin family of proteins, which are highly conserved and play critical roles in cell motility, structure, and integrity.
Alpha, beta, and gamma actin isoforms have been identified:
- Alpha actins: Major constituents of the contractile apparatus
- Beta and gamma actins: Involved in the regulation of cell motility
This actin is an alpha actin found in skeletal muscle.
Mutations in this gene are associated with:
- Nemaline myopathy type 3
- Congenital myopathy with excess thin myofilaments
- Congenital myopathy with cores
- Congenital myopathy with fiber-type disproportion
These conditions lead to muscle fiber defects.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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