Thermo Fisher Scientific ACTA1/ACTA2/ACTC1 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:2,000

-

Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

A synthesized peptide derived from human ACTA1(Accession P68133), corresponding to amino acid residues M1-P34. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:ACTA1/ACTA2/ACTC1,uniProtId:P68133-1,ncbiNodeId:9606,antigenRange:1|1-34,antigenLength:377,antigenImageFileName:PA5-100907_ACTA1ACTA2ACTC1_P68133-1_Rabbit.svg,antigenImageFileNamePDP:PA5-100907_ACTA1ACTA2ACTC1_P68133-1_Rabbit_PDP.jpeg,sortOrder:1},{targetFamily:ACTA1/ACTA2/ACTC1,uniProtId:P68032-1,ncbiNodeId:9606,antigenRange:1,antigenLength:377,antigenImageFileName:PA5-100907_ACTA1ACTA2ACTC1_P68032-1_Rabbit.svg,antigenImageFileNamePDP:PA5-100907_ACTA1ACTA2ACTC1_P68032-1_Rabbit_PDP.jpeg,sortOrder:2}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Affinity chromatography

Storage buffer

PBS, pH 7.4, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice

RRID

AB_2815832

Product Specific Information

Antibody detects endogenous levels of total ACTA1/A2/C1.

Target Information

The product encoded by this gene belongs to the actin family of proteins, which are highly conserved proteins that play a role in cell motility, structure and integrity. Alpha, beta and gamma actin isoforms have been identified, with alpha actins being a major constituent of the contractile apparatus, while beta and gamma actins are involved in the regulation of cell motility. This actin is an alpha actin that is found in skeletal muscle. Mutations in this gene cause nemaline myopathy type 3, congenital myopathy with excess of thin myofilaments, congenital myopathy with cores, and congenital myopathy with fiber-type disproportion, diseases that lead to muscle fiber defects.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.