Thermo Fisher Scientific FGF19 Polyclonal Antibody
FGF19 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot과 IHC(P)에서 사용 가능. Human 및 Rat 시료에 반응하며, Affinity chromatography로 정제됨. PBS/glycerol 완충액에 보관되며 -20°C에서 저장 권장.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human FGF19 (Accession O95750), corresponding to amino acid residues M168–K216 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2850399 |
Product Specific Information
This antibody detects endogenous levels of total FGF19.
Target Information
FGF19 (Fibroblast Growth Factor 19) is a protein encoded by the FGF19 gene in humans, located on chromosome 11q13.3. The 216-amino acid FGF19 protein includes a signal sequence and two conserved cysteine residues typical of the FGF family. Expression is found in fetal brain tissue but not in adult brain. FGF19 stimulates hepatic protein and glycogen synthesis independently of insulin or Akt pathways, acting through the MAP kinase signaling cascade. The mouse ortholog, FGF15, shares approximately 50% amino acid identity and exhibits similar biological functions.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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