Octet R8 Protein Analysis Systems

Octet R8 Protein Analysis Systems

High Throughput System for Biologics Discovery, Development, QC, and Manufacturing

The Octet® R8 label-free protein analysis system provides fast, high throughput, and accurate characterization of biomolecules. It supports long experimental run times and seamless integration into GxP-compliant labs during biologics development.

The 8-channel Octet® R8 system performs quantitation and kinetic analysis of up to 96 samples in 30 minutes to 2.5 hours, depending on the assay. An optional microplate evaporation cover minimizes sample loss and allows post-analysis recovery.

Key Features

• Unmatched Flexibility and Versatility: Eight parallel, independent channels for maximum speed, sensitivity, and flexibility
• Unattended Run Time: Optional evaporation cover enables up to 12 hours of unattended operation
• GxP Upgrade Option: Available with 21 CFR Part 11 software, IQOQPQ kits, and regulatory compliance services

Benefits of the Octet® R8 System

High-Quality Kinetic Screening and Affinity Characterization
Real-time monitoring of binding events to calculate on rates (ka), off rates (kd), and affinity constants (KD).

Versatility to Detect a Wide Range of Molecules
Detects diverse biomolecules from small molecules to proteins and cells.

Eight Parallel, Independent Channels
Independent or paired channel operation for screening or reference-based kinetic characterization.

GxP-Ready Operation
Optional 21 CFR Part 11 software and qualification kits for regulated environments.

Sample Plate Cooling (15–40°C)
Temperature control for reliable kinetic determinations and thermodynamic analysis of temperature-sensitive proteins.

Fluidics-Free Dip and Read Format
Reduces assay time and maintenance costs. Compatible with crude samples and allows non-destructive testing.

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Applications

Kinetic and Affinity Characterization

Measures kinetic constants for small and large molecules without microfluidics. Ready-to-use biosensors streamline workflows and enable direct crude sample measurement.

Protein Quantitation in Bioprocessing

Quantifies protein concentrations in as little as 2 minutes per sample or 32 minutes for a 96-well plate. Sub-ng/mL sensitivity achievable with multi-step assays. Biosensors can be regenerated and reused for improved process economy.

Quality Control (QC) and Manufacturing

Designed for regulated QC environments. Supports method development, validation, lot release, and impurity analysis. Combined with 21 CFR Part 11 software and GxP services for compliant labs.

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Technical Specifications

항목	내용
채널 수	8 parallel, independent channels
분석 모드	Quantitation, Kinetic Analysis
샘플 처리량	최대 96 samples / 30 min–2.5 hr
온도 제어 범위	15–40°C
운영 방식	Fluidics-free Dip and Read
GxP 호환성	Optional 21 CFR Part 11 software, IQOQ/PQ kits
무인 운전 시간	최대 12시간 (Evaporation Cover 사용 시)
주요 응용 분야	Biologics discovery, QC, manufacturing, immunoassay development, epitope mapping, ligand binding, small molecule analysis

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